BT&C, Inc., Offering creative and innovative solutions to our customers for over 23 years.


BT&C Inc.

291 Route 22 East

Building 6

Lebanon, NJ 08833

TEL: (908) 253-3444

FAX: (908) 575-1660

About BT&C

Contact Us

Contract Research

Product Development
Custom Training


Cytophobic Cultureware

Keratinocyte Harvesting

Defective Toy

Absent Scientists


Homogenizer Comparison

Low Binding Beads

Cell Based Assays

High Throughput Grinding

DNA Isolation from Soybeans

Aseptic Freeze Drying

Cryogenic Storage

Homogenization Guide

Maintenance of Protein Stability

OPS Diagnostics
Custom Products

New Products

Online Store




David W. Burden, Ph.D., President

Dr. Burden founded Biotechnology Training & Consulting (BT and C) in 1987 in response to the demand for technical support and training in the biotechnology/pharmaceutical industry. In this realm, he has worked as a biotechnology consultant and educator since 1984. His research interests are in microbial gene expression as relates to physiology, while consulting interests include projects in product application development, assay development, bioremediation, and product/process troubleshooting. He is versed in microbiology, molecular genetics, and separation. 


Dr. Burden co-authored the book "Biotechnology: Proteins to PCR" and is editor of the Biotechnology Training Institute Series of technical manuals. Dr. Burden earned a doctorate in Microbiology and Molecular Genetics from Rutgers University.


The following is a summary of Dr. Burden's background.


Research Experience

1/90 - Present, Contract Scientist, BT and C, Inc., Life Science Contract Research and Consulting, Bridgewater, NJ

Contract research was the principle activity of BT and C by the late 1990s. Projects listed in appendix. Major efforts include:

  • Establishment of a research program for a novel nucleic acid detection system
  • Recruited, trained, and supervised scientific and support staff
  • Implemented SOPs and quality control processes for contract research and routine operation
  • Served as a virtual research and development department for clients
  • Developed novel cell-based assays to study immune response and wound healing
  • Performed contract research in high throughput screening, cloning, microbiology, biomaterials, cell culture, immunoassays, and DNA diagnostics.
  • Business/Management Experience

    1/87 - Present, President, BT and C, Inc., Life Science Contract Research and Consulting, Bridgewater, NJ

    BT and C was originally established as a biotechnology continuing education organization and evolved into contract research and consulting services. Major accomplishments:

  • Established business from scratch without loans or external investment
  • Increased sales an average of 15% over first six years of operation
  • Designed and implemented marketing plan for consulting and contract business
  • Served as scientific marketing consultant
  • 11/98 - Present, Principal, OPS Diagnostics, LLC, Custom Laboratory Products, Bridgewater, NJ

    OPS Diagnostics was founded as an avenue for developing scientific products with commercial applications. Major accomplishments:

  • Established sales and distribution relationships within the sample preparation market
  • Developed products, including manufacturing and quality control processes
  • Negotiated shared equity relationships on co-developed products
  • Cultivated client relationships for equipment and customized consumable products
  • 10/96 - 12/99, Chairman, Scientific Advisory Group/Acting Vice-President, Sales and Marketing, Revco Technologies, A Division of SPX Corporation, Asheville, NC

  • Initiated the Scientific Advisory Group for Revco Technologies so to provide advice and guidance to the management team
  • Devised distribution mechanism to increase sales of poorly performing brands
  • Identified new markets for existing products and adjusted sales efforts accordingly
  • Served as interim VP of Sales and Marketing
  • Teaching/Educational Experience

    1/84 - 10/99, Continuing Professional Educator through Rutgers University and BT and C, Inc.

  • Responsible for organizing, developing, and instructing hundreds of workshops over the past two decades. Major accomplishments include:
  • Generated hands-on training programs in the life sciences. Developed manuals used to train over 1500 science and business professionals
  • Established the Biotechnology Training Institute, May 1991, as a training facility
  • Developed and managed State of New Jersey training program and licensing exam for environmental health specialists offered through Rutgers University
  • 8/86 - 6/91,  Resident Counselor, Cook College, Rutgers University, New Brunswick, NJ

    9/84 - 8/89,  Graduate & Teaching Assistant/Instructor, Department of Biochemistry and Microbiology, Cook College, Rutgers University, New Brunswick, NJ

    11/82 - 6/84,  Chemistry and Biology Teacher, Dunellen High School, Dunellen, NJ

    12/81 - 6/82, Biology and Marine Science Teacher, Watchung Hills Regional High School, Warren, NJ


    Doctor of Philosophy in Microbiology and Molecular Genetics, January 1994, University of Medicine and Dentistry of New Jersey/Rutgers-The State University of New Jersey, New Brunswick, NJ 08903

    Major Professor: Dr. Douglas E. Eveleigh, Professor of Microbiology

    Thesis: Physiology and Expression of MEL1 in Wild Type and Engineered Yeasts.

    Bachelor of Science in Biology/Microbiology, May 1981, Cook College, Rutgers-The State University of New Jersey, New Brunswick, NJ 08903

    Certification: Teacher of Science (Comprehensive K-12)

    Honors - George H. Cook Scholar, Dean's List (78-81), Alpha Tau Alpha (President)


  • Isothermal Nucleic Amplification System: Cited in continuance

  • Novel System for the Detection and Differentiation of PCR Products: Filed by and based on research at BT&C, Inc.
  • Devices and Methods for Reducing Variability in Cell-Based and In Vitro Assays Employing Improved Methods for the Control of Extrinsic Parameters: Device and methods developed at BT&C, Inc., for third party.
  • Professional Involvement

  • Theobald Smith Society, Local ASM Chapter, Counselor - 2000-2003.

  • General Signal Laboratory Equipment, Scientific Advisory Group, Chairman, 1996-2000.
  • American Society for Microbiology, Member since 1987.
  • Cook College Financial Aid Committee - 1986 to 1989.
  • Environment & Public Health Ad Hoc Committee - 1984 to 1989.
  • Environment & Public Health Curriculum Development Committee - 1988 to 1989.
  • NJ State Sanitarian Licensing Exam Development Committee - 1987 to 1989.
  • Publications & Abstracts

    Piorkowski, A., G. Vaghani, W. Fithian, and D. Burden. 2002. Evaluation of methods for the high-throughput mechanical disruption of biological samples for nucleic acid extraction. Plant, Animal & Microbe Genomes X Conference, January, San Diego, CA.

    Zhang, P., C.J. Gebhart, D. Burden, and G.E. Duhamel. 2000. Improved diagnosis of porcine enteropathy caused by Lawsonia intracellularis using polymerase chain reaction-enzyme-linked oligosorbent assay (PCR-ELOSA). Molecular & Cellular Probes Apr 14(3): 101-8.

    Zhang, P., C.J. Gebhart, M.R. Mathiesen, D. Burden, and G.E. Duhamel. 1999. Diagnosis of porcine proliferative enteropathy caused by Lawsonia intracellularis using polymerase chain reaction-enzyme-linked oligosorbent assay (PCR-ELOSA). Eightieth Conference of Research Workers in Animal Diseases. November, Chicago, IL.

    Burden, D.W., C.O. Daus, C. Lamb, and C. Grant. 1998. Parameters affecting the variability of cell based assays. Annual Meeting of the American Society for Microbiology. May. Atlanta, GA.

    Burden, D.W. and D. Whitney. 1995. Biotechnology: Proteins to PCR. Birkhäuser, Boston.

    Burden, D.W. and D.E. Eveleigh. 1990. The effect of deleting the MEL1 UASG on the expression of galactose utilization. Annual Meeting of the American Society for Microbiology. May. Anaheim, CA.

    Burden, D.W. and D.E. Eveleigh. 1990. Yeasts - Diverse substrates and products. In: J.F.T. Spencer and D.M. Spencer (eds.), Yeast Technology. Springer-Verlag, Berlin, pp 199-227.

    Burden, D.W. 1989. Development of a comprehensive sanitarian training program in New Jersey. National Environ. Health Assoc. Annual Convention. June. Seattle, WA.

    Burden, D., J.A. Cuccurullo, and D.E. Eveleigh. 1989. Expression of indigenous and recombinant melibiase genes in yeast fermentations with mixed carbon sources. Annual Meeting of the American Society for Microbiology. May. New Orleans. LA.

    Burden, D.W. and D.E. Eveleigh. 1987. Construction of a petite, G418 resistant Saccharomyces uvarum. Society for Industrial Microbiology Annual Convention. August. Baltimore, MD.


    “Molecular Biology Methods for Biomaterials Evaluation.” April 22, 1998. Society for Biomaterials Annual Meeting, San Diego, CA. Invited speaker.

    “Covalent Immobilization of Oligonucleotides to Pre-activated Surfaces for Use in Rapid DNA Probe Assays.” April 16, 1996. 1996 Experimental Biology Annual Meeting, Washington, DC.

    “Sanitarians: Are they born or created? A review of the Rutgers Environment & Public Health training course.” January 19, 1989. New Jersey Health Officers Assoc., General Membership Meeting. Flemington, NJ

    Recombinant DNA Techniques: An Introductory Laboratory Course. August 1990. Office of Professional Continuing Education, Cook College, Rutgers University, New Brunswick, NJ. Also held 6/90, 1/90, 10/89, 6/89, 1/89, 6/88, 1/88, 8/87, and 1/87.

    Interdisciplinary Environmental Education Workshop at Nantucket, MA. April 8-12, 1985. Office of Professional Continuing Education, Cook College, Rutgers University, New Brunswick, NJ. Also held 4/80 and 4/79.


    Dr. David W. Burden, President of BT&C, visiting with the first three computers used to start the business.